Background: To assess clinical and radiological association of carcinoma larynx and hypopharynx. Materials & Methods: 100 patients with newly diagnosed carcinoma of larynx and hypopharynx were included in the study. Complete demographic and clinical details of all the patients was recorded. Biopsy was done by direct endoscopic examination either under LA or GA. Clinical TNM staging based on this information was made. Correlation of clinical findings with radiographic findings was done. All the results were recorded and analysed using SPSS software. Results: While assessing the distribution of patients according to tumour size as per clinical evaluation, it was seen that 29 percent and 25 percent of the patients were of T3 and T2 staging while 23 percent of the patients each were of T1 and T4 staging respectively. On radiographic evaluation, it was seen that 5 patients which were diagnosed as T2 clinically, were found to be of T3 (2 patients) and T4 (3 patients). While analysing the correlation statistically, significant results were obtained. Conclusion: A combination of clinical and radiological assessment in carcinoma of larynx and hypopharynx is necessary so that prompt treatment can be given.