Background: Tuberculosis has resurged and remained a major worldwide health problem. Although Mycobacterium tuberculosis can involve any organ, most commonly the lung, central nervous system (CNS) tuberculosis is the most devastating form of the disease. Approximately 5-10% of all patients with tuberculosis and up to 20% of patients with AIDSrelated tuberculosis have CNS involvement. Central nervous system (CNS) tuberculosis is a potentially life-threatening condition which is curable if the correct diagnosis is made in the early stages. Its clinical and radiologic manifestations may mimic other infectious and noninfectious neurological conditions. Hence, familiarity with the imaging presentations of various forms of CNS tuberculosis is essential in timely diagnosis, and thereby reducing the morbidity and mortality of this disease.