Background: Obstructive sleep apnea (OSA) is being recognized as an important public health problem worldwide. The timely diagnosis and treatment of OSA with underlying etiology leads to decreased symptoms and increases quality of life among OSA patients. Present study was aimed to study clinical profile of patients with obstructive sleep apnea attending tertiary care hospital. Material and Methods: Present study was singlecenter, prospective, observational study, conducted in patients more than 18 years of age, had symptoms suggestive of Sleep Disordered Breathing such as, excessive daytime somnolence, disruptive snoring, fragmented sleep, choking and gasping, un-refreshing sleep, morning headache, personality changes and Impaired concentration, insomnia, daytime headache.