Deoxyribonucleic acid called DNA is the littlest essential unit that bears the hereditary directions of a living being. Due to increase in genomic data, increases the storage capacity of that data being stored. In order to process the massive amount of genomic data, there is a need of an effectual depository for quick transposal and achieve preferable performance while processing that data. In this paper, introduced a novel compression algorithm without using much complicated computation for compression of DNA sequences.The result in terms of compression magnitude relation in bits/base and also the compression/decompression time has been compared with the present approaches conferred within the literatures. Our algorithmic rule produces higher compression quantitative relation and utilizes terribly less time to compress and decompress the genomic sequences and additionally there's no further storage needed for compression and decompression.