Online ISSN: 2515-8260

Comparative Analysis of Cell Block Method and Smear Examination in FNAC Aspirates for Diagnostic Utility in Tertiary Care Centre, Jaipur, Rajasthan

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1Dr. Naresh N Rai, 2Dr. Murari Lal Dhanetwal, 3Dr. Kailash Prajapat, 4Dr. Ajay Kumar Gupta, 5Dr. Anju Arya


Introduction: Fine needle aspiration (FNA) cytology, which provides a very quick preliminary diagnosis with no harm to the patient and at a far cheaper cost than surgical biopsy, is commonly utilized in the analysis of lesions from diverse body sites. The ability to quickly and accurately diagnose with little invasiveness with FNAC is crucial. Materials & Methods: All patients with clinically enlarged peripheral swellings who presented to the pathology department are included. All FNAC samples of enlarged peripheral swellings were used to prepare air dried and alcohol fixed CSs to be stained with MGG stain or H&E stain respectively and to prepare CB by Plasma - Thromboplastin method and the sections were stained with H&E and specific stain as per diagnostic requirement. Results: A total of 51 patients were enrolled in this study between the Age of 10 to 90 yrs. The mean age of present study participants was 46.27± 18.43 year and cases within the age range of 46-60 years (31.4%) constituted the largest group. In the Conventional smear benign cases were 23.5% while in CB it was 21.6% observed. Malignancies were found in 37.3% while in CB it was reported 25.5%. This distribution was statistically significant (p value<0.05). Conclusion: The current study conclude that CS has a good correlation with malignant lesions, with adequate cellularity, clear visibility of nucleus and cytoplasm and wellpreserved architecture. However, blood obscuring and cellular degeneration is encountered more frequently. CB can hence be used as a supplement in arriving at an accurate diagnosis.

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