Pain And Inflammation Are Disabling Accompaniments Of Many Medical Conditions. So, Controlling Both Pain And Inflammation Assumes The Top Priority For The Physician. Inflammation Is A Part Of A Complex Biological Response Of Vascular Tissues To Harmful Stimuli Such As Pathogens, Chemicals Or Irritants. Therapy Of Pain And Inflammation Has Always Been Debatable. Methods: Rats Were Divided Into 10 Groups Of 6 Animals Of Each. The Antiinflammatory Activity Was Studied With Carrageenan Induced Rat Paw Edema Models. The Analgesic Activity Was Evaluated Using Tail Flick And Eddy’s Hot Plate Model. The Ethanolic Extract Of Balanitesa Egyptiaca Whole Plant Preparations Were Compared With Indomethacine In Both Acute And Sub Acute Inflammatory Models. The As 400 Mg/Kg Show Significant Increase In Latency To Tail Flick And Eddy’s Hot Plate Method Compared To Control Group (P > 0.05). The Highest Nociception Inhibition Of Stimulus By As 400 Mg/Kg (400 Mg/Kg) Was Observed Up To 180 Minutes. Various Test Result Parameters Were Statistically Analysed At P Value. The Present Results Suggest That Ethanolic Extract Of Balanitesa Egyptiaca Suppresses The First Phase Of Carrageenan-Induced Paw Edema, Thus, Confirming An Nsaid-Like Property.