Background: Pulp necrosis denotes the cessation of the metabolic processes of this tissue, with consequent loss of its structure, as well as its natural defenses. A great variety of endodontic sealers are available commercially and they are divided into different groups according to their chemical composition (Eg: Zinc oxide eugenol based, MTA based, Epoxy resin based). Hence; the present study was undertaken for comparing the marginal adaptation of epoxy resin based sealer (AH Plus) and MTA based sealer (MTA Fillapex) at dentin sealer interface at apical one third of the root canals. Materials & methods: 50 Straight maxillary central incisors (each root with curvature less than 5◦ ), free from any open apices, cracks, calcified canals, canal curvature, and resorptive defects teeth were used. The canals were dried with absorbent paper points and were randomized into two groups of 25 teeth each, as following. Group 1: Obturation using AH PLUS, and Group 2: Obturation using MTA fillapex. All the sample teeth were obturated using single cone obturation technique. All specimens were dehydrated using aqueous ethanol and then were gold sputtered. Specimens were observed under Scanning Electron Microscope (SEM). Overall average gaps at this interface were calculated for each sample and results were tabulated. Results: Mean marginal adaptation at the apical end among the specimens of group 1 and group 2 was 1.86 and 0.53 respectively. Mean marginal adaptation at the coronal end among the specimens of group 1 and group 2 was 2.86 and 0.56 respectively. While analysing statistically, it was seen that mean marginal adaptation was significantly among specimens of group 1 in comparison to group 2 Conclusion: Marginal adaptability of AH PLUS was significantly higher in comparison to specimens of MTA fillapex group.