Chronic rhinosinusitis (CRS) is infection or inflammation of nasal airway and paranasal sinuses, the etiology of this disorder in multifactorial. CRS is directly related to threatened cardiovascular complications, Hypertension is one of the common chronic disorders that has great effect on the heart and blood vessels. In this prospective clinical study, we attempt to find the relationship between hypertension and CRS by investigated 2 groups of adult patients. The first group is composed of 100 patients of both sexes suffering from chronic rhinosinusitis compared to the second group (control) composed of 100 individuals who are healthy. The results refer that there is an important increase in the blood pressure in group 1 especially above 50 years compare to control group. This study found that CRS has important effect on blood pressure especially in men.