The article examines the issue of the formation and development of handicraft production in one of the large ancient settlements of the medieval South Aral region Mizdakhkan. The settlement during this period was the center of the agro-industrial complex, since, first of all, handicraft production developed here. Stationary archaeological excavations in the medieval quarters of the settlement have shown the high development of industries of the handicraft complex, such as pottery, glass and bone carving, weaving, stone-cutting art, metalworking, leatherworking and other industries that produced the necessary goods in the everyday life of the feudal society and provided high-quality tools to the adjacent foreign cities in the medieval period