Abstract: After the operation for gangrenous - perforated appendicitis, miscarriage occurs in 11%, infertility in 62% of cases. 154 girls aged 3 to 15 years were examined. For the purpose of diagnosis, a complex of examinations was carried out: collection of anamnesis data, analysis of menstrual and generative functions, bimanual examination, colposcopy, microbiological examination of the contents of the cervical canal and vagina, polymerase chain reaction to reveal sexually transmitted diseases, assessment of the functional state of the ovaries, examination of the sexual partner , hormonal examination, ultrasonic examination of small pelvis organs and thyroid gland, examination of the mammary glands. The developed algorithm makes it possible to carry out timely diagnosis and treatment of complications of reproductive function in girls after suffering from prevalent appendicular peritonitis.