Abstract: Homoeopathy has to play major role in future of World’s health as the whole world is worst hit by pandemic of CORONA VIRUS.Homeopathic prophylactic medicines are based on the ability to prevent infective diseases & boost one’s immunity when chosen according to the principle of similarity.This historicreview was the ground for evaluating the response to treatment including homeopathy in the former epidemics and also try to emphasize on future role Homoeopathy.