Aim: Purpose of our research was to assess the outcome as well as correlation after extraction of four premolar teeth for orthodontic treatment and will it result in dished in facial profile. Methodology: Pretreatment and posttreatment records of 73 patients were chosen at random from completed cases in the practice of one experienced orthodontist. Eighteen involved the extraction of upper first premolars, and 55 involved the extraction of upper second premolars. Of these 55, 29 involved the extraction of upper first premolars and 26 involved the extraction of upper second premolars. In the upper first premolar group, however, all 18 involved the extraction of upper first premolars. Pretreatment factors that recommended a foundation for the extraction option in this group of patients who had incisal overjet, molar relationship, and fundamental upright facial outline. Results: A wide variety of arch dimensional changes was found with different upper premolar extraction patterns. There was evidence, however, of more intermolar arch width reduction after the extraction of upper second premolars than upper first premolars. Orthodontic treatment with the extraction of premolars did not steadily cause a retraction effect on the incisors. In fact, examples of proclination of the incisors happened inside all of the extraction groups. Conclusion: A large amount of individual variation in incisor and molar changes accompanied treatment involving all upper premolar extraction patterns but It didn’t result in dished facial profile in our study.