Background Emotionally immature children are more likely to develop health problems, including dental problems. Dental treatments require a good level of communication with the patient. Therefore, in these patients, sedation and general anesthesia are an extremely humanistic approach for comfortable and successful treatment. In such children, there is no standard anesthetic approach due to varying clinical conditions. The aim of this study was to compare general anesthesia and sedation during dental treatment of such children. Methods 25 children with greater than 16 score on Rutters Child Behaviour Scale were treated under general anesthesia or sedation. Demographic data, the American Society of Anesthesiologists classification, Mallampati score, anesthesia duration, anesthesia type, anesthetic and analgesic agents used, dental treatment performed, secondary diseases, and complications in the perioperative period were recorded. Results From 25 children (12 females, 13 males) that were treated during February 2016 and December 2019, 13 were treated under GA, their mean age at the time of the post treatment examination was 48±11 months, and the mean time lapse after treatment was 14.5±6.2 months. The group treated by sedation (Pental Sodium and Propofol) included 12 children, with a mean age of 56±11.6 months at the time of the post treatment examination, and a mean time lapse after treatment of 16.5±5.03 months. Conclusion Both the anesthetic approaches shows better results with no complications reported post treatment. Hence can be effectively used in emotionally immature children.