Aims and objectives: The present study will be aimed to assess the Horizontal and vertical bone loss before and after active orthodontic treatment in 105 patients in the city of Alkharj, Riyadh region of the Kingdom of Saudi Arabia. Materials and methods: Pre and post orthodontic treatment OPG of 105 patients were selected form clinics in random from the Riyadh region of the kingdom of Saudi Arabia for the study. Descriptive statistics, analysis of variance, Scheffe post hoc analysis for group comparison, and level of significance. Results: When the OPG of 105 samples were studied, a statistically significant values and results [P<0.05]were revealed with relation to bone loss in upper left posterior area, bone loss in upper right posterior area, bone loss in lower left posterior area, bone loss in lower anterior area and bone loss in lower right posterior area before and after orthodontic treatment.