Online ISSN: 2515-8260
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“Initial laboratorycharacteristics and treatment relatedfactors in relation to occurrence of cerebral edema in children with diabetic Ketoacidosis- experience of a tertiary care center”

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Dr Rajesh Kumar, 1Dr Sadhana Kumari,2Dr Vikash Chandra,3Dr (Prof) Alka Singh, 4 Dr Md Athar Ansari, 5Dr Girijanand Jha6

Abstract

Background and Objectives: The most gruesome complication of DKA is cerebral edema (CE) as it is not only associated with a high mortality ratebut also leads to significant morbidity among the survivors. Therefore, it is prudent that clinicians emphasise on its early recognition so as to intervene quickly and timely. The present study was undertaken to study the association between cerebral edema and demographic features, initial laboratory characteristics and treatment related factors in children presenting with DKA at a tertiary care institute. Methodology: This hospital-based cohort study was conducted in Paediatrics department of our hospital overthree years fromOctober 2019 to September 20222 including children >1 year to <15 years of age presenting to I.P.D or Emergency with DKA. Classification of DKA was done as per ISPAD 2018 guideline and cerebral edema was diagnosed on pre-set clinical criteria. Children with incomplete information regarding their treatment immediately prior to admission at our institute were excluded.

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