Online ISSN: 2515-8260

Innovative Methods of Elementosis Study in Oncourological Practice

Main Article Content

Tatyana V. Pavlova1 , Vladimir F. Kulikovsky1 , Natalia B. Pilkevich1 , Lyubov A. Pavlova1 , Dmitry V. Bessmertnyy2 , Ivan A. Pavlov2


ABSTRACT The purpose of this work is to study the content of macronutrients in the tissues with oncourological pathology. Methods: Clinical examination material of 279 people was used in the work, 229 of them were men (82%) and 50 were women (18%). Elemental analysis of oxygen, carbon, calcium, nitrogen and sulfur was carried out using a detector to record the spectra of characteristic X-ray radiation (EPAX company), which were integrated with "Quanta 600 FEG" scanning electron microscope. Results: with prostate cancer, the oxygen content decreased, so during stage 1, the oxygen content decreased by 36.8% among middle-aged patients, and by 38.6% among elderly patients, stage 2 - by 32.4% and 28.9%, stage 3 - by 34.1% and 34.2%, and stage 4 - by 30.9% and 35.1%. The nitrogen content changed insignificantly, carbon and sulfur decreased. The calcium index among middle-aged patients with stage 1 prostate cancer increases by 10.6, and by 10.8 times among the elderly, while it is absent among the patients with stage 2, 3 and 4. The nitrogen content among the patients with renal pathology did not change significantly, but there was a tendency of carbon, calcium, and sulfur increase and oxygen decrease. When they studied the level of macronutrients in bladder cancer, there was a tendency to nitrogen and carbon level increase, and in the groups of stage 1 and 2 patients, the content of calcium and sulfur increased by 12.5 and 3.8 times, respectively, and oxygen was also reduced. Conclusions: we found that all groups demonstrated oxygen content decrease, most pronounced among stage 2 patients with bladder cancer - 49.5%, which leads to tissue hypoxia in the studied organs. The nitrogen and carbon content varied slightly. The content of calcium and sulfur increases among the patients of all studied groups.

Article Details