Online ISSN: 2515-8260

Intrahepatic cholestasis of pregnancy prevalence and feto maternal outcome

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Dr.Eeshadi Divya1 , Dr.Smita Rai2 , Dr.Neetu Singh3

Abstract

Background:Cholestasis is defined as impairment of bile flow due to intrahepatic or extrahepatic causes, leading to retention of hepatotoxic compounds; specifically bile acids. The present study was conducted to evaluate the feto-maternal outcome in patients with intrahepatic cholestasis of pregnancy. Materials & Methods:It included 190 subjects in the study. Group A consisted of 95 women who presented with pruritis in their second & third trimester of pregnancy with associated abnormal liver function in the absence of other liver and skin disease. 95 women with uncomplicated pregnancy and no history of pruritis& with normal liver function test were taken as Group B/control.

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