Cariogenic Microorganisms Can Be Described By Their Ability To Colonize On Tooth Surfaces, Causing A Marked Reduction Of Ph In Presence Of A Sugar Substrate And Consequently Induce Dental Caries. Streptococcus Mutans, Streptococcus Sanguinis, Lactobacillus Casei And Actintinomyces Viscosus Fulfil Most Of These Criteria. This Study Looked At The Relationship Between Mutans Streptococci, Lactobacillus, Actinomyces In Saliva Collected From Tooth Sites In Three Ethnic Groups, With Rampant Caries, Individual With Single Caries And Without Caries. All Samples Were Collected And Cultured Onto Selective Media. Colonies Were Enumerated And Identified Using Biochemical Tests. ‘Descriptive Statistical Analysis’ (I.E. Mean, Standard Deviation And Standard Error) Was Carried Out For All The Groups In This Study. A Higher Mean Microbial Count Was Observed In Individuals With Rampant Caries, Than Individuals With Single Caries And Was Least In The Control Group. Hence, Oral Microbes Are In Constant Flux But Have Interrelationships In Children With Caries.