Online ISSN: 2515-8260

Liver Function Tests to Predict the Severity of Dengue Fever in Serologically Positive Children Below 18 Years of Age

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Janardhan Reddy Pulluru1 , Suraboina Satishkumar2 , Gajula Ravi3

Abstract

Background:Dengue fever presents with a diverse clinical spectrum. Although liver is not a major target organ, hepatic dysfunction is a well recognized feature. In this study we attempted to study the pattern of hepatic involvement in children with dengue and its association with disease severity. Materials and Methods: This was a cross sectional study conducted at during the period of 1 year. Children <18 years of age with dengue Ns1 Ag and IgM positive were included in this study. After obtaining informed consent, a pre structured proforma was used to record the relevant information from each subject. After detailed clinical examination and haematological investigation children were categorized into three groups as dengue fever with no warning signs(DNWS), dengue fever with warning signs(DWWS) and severe dengue fever(SDF) according to WHO classification. Statistical analysis was done to know the strength of association between different clinical and biochemical variables and outcome of the disease

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