Aim: To compared the oxiport laryngoscope blade versus miller laryngoscope blade for intubation in neonates and infants during general anesthesia. Methods: This controlled interventional single-blind study conducted in the, Department of Anesthesiology. 60 neonates/infants in groups of 30 each posted for surgery in paediatric operation theatre over a period of 6 months were included in the study. Full-term neonates and infants up to 6 months of age of either sex requiring general anaesthesia with endotracheal intubation for elective as well as emergency surgery were included in the study