Online ISSN: 2515-8260
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PHYTOCHEMICALS INVESTIGATION OF ANTIOXIDANT, ANTICANCER ACTIVITY OF DRY FRUIT EXTRACT OF FICUS CARICA LINN IN EXPERIMENTAL ANIMALS

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HAQUE MUDABBIRUL1* , SHIRSAT MRUNAL KRISHNARAO2 , KAYANDE NANDU3 , AEJAZ AHMED

Abstract

The antioxidant and anticancer activity dry fruit extract of ficus carica linn investigated against free radical scavenging activity (RSA) [reactions with 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and anticancer activity against Dalton’s ascitic lymphoma cell line and assessment of the influence of extracts on the enzyme xanthine oxidase (XO), and Fe3+ reducing ability. Antitumor activity was studied on swiss albino mice at various dose such as 250, 500, and 1000 mg/kg, body weight. The experimental parameter used were tumor volume, tumor cell count, viable tumor cell count, mean survival time and increase in life span to assess antitumor activity

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