Nightmares along with happy dreams is the scenario of parents of congenital anomalies child. Antenatal diagnosis of congenital anomalies need high index of clinical suspicion. If suspected on ultrasound, further investigation be should be carried out to find out any chromosomal defects. Genetic counselling plays crucial role in chromosomal anomalies. Here we present a spectrum of congenital anomalies of brain and spinal cord at various stages of development.