The placement of immediate implants in the fresh extraction sockets of infected teeth with periradicular/ periapical lesions is contraindicated because of the infection with subsequent loss of bone essential for implant placement. A 47-year-old female patient reported to the clinic with multiple carious and missing teeth. The patients also had numerous faulty restorations. Tooth # 14 showed a sizeable periapical defect which would compromise the success of the implant. Hence, it was decided to prepare the implant site by interim endodontic therapy. The implant site healed postendodontic treatment, and an immediate implant was placed. The provisional treatment improved for the most part prognosis of the patient’s dental care. When treated, the hopeless teeth can serve many preventive, biologic, and aesthetic functions. The reported case has clinically demonstrated that interim endodontic implant site preparation, when performed correctly can eliminate the hopeless tooth infection, regenerate bone and facilitate satisfactory immediate implant placement. Hence, this approach can be used as an alternative to hopeless tooth extraction and limiting the disadvantages associated with tissue regeneration procedures.