Background: The present study was undertaken for assessing the quality of life in patients with breast cancer before and after diagnosis. Materials & methods: 200 patients were enrolled for the present study. A complete demographic and clinical detail of all the patients was obtained. At the baseline stage, interview was conducted among all the patients after obtaining their prior consent. This interview was conducted with the aim of gathering data in relation to quality of life. Afterwards, 100 patients that had confirmed histopathological diagnosis of breast cancer were separated and remaining all the patients was excluded. Follow-up of all the patients was done and re-interview of all the patients was again carried out. All the results were recorded and analysed using SPSS software.