A study has conducted to explore the relationship between the total Institution and drug addicts’ rehabilitation at Milo Shaheed Trust Quetta. The study aims to analyses the significance of closed environment and rehabilitation of drug addicts. Inmates are de-socialize and re-socialize in Milo Shaheed Trust. In this survey, an open and close ended interview is conducted by two staff members and fifteen patients of the trust for the qualitative nature of information. This study highlights the drug addicts’ daily life in total institution and different treatments for the drug addicts. Furthermore, it has been observed that the role of trust as total institution for resocialization is crucial by the help of Institution and patient’s family. There are many members that are re-socialized and offer their social duties of the daily routine of life.