With continuous advancement of society and rapidly development of science and technology, the Internet has become popular in all walks of life in society, especially in the medical system. Under the new situation, a traditional medical system has been unable to adapt to the current working methods and modern medical management system. In order to improve efficiency and quality of nursing management,in-hospital information network management can be implementedthrough establishment of nursing management network information system. As a result,the application of nursing management information system improves nursing management ability and work efficiency, saves cost of nursing management, and improves patients’ satisfaction.