Online ISSN: 2515-8260
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RESULTS OF MOLECULAR GENETIC ANALYSIS OF MTR AND MTRR GENES IN CHILDREN WITH AUTISM

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Majidova Yakutkhan, Farangisbonu Doniyorova, Nargiza Ergasheva

Abstract

Abstract: Statistically significant association of allele G and hetero A/G, homozygous genotype G/G polymorphism rs1801394 MTRR gene with risk of autism development was revealed. The presence of allele A and genotype A/A polymorphism of the rs1801394 MTRR gene reduces the risk of autism. Identification of allele G increased the risk of autism by 1.4 times compared to the presence of allele A (95% CI = 0.68-2.93, df=1). The presence of the allele G of MTR A2756G polymorphism correlates with an increased risk of autism.

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