Aims and objectives: To study the role of Magnetic Resonance Imaging in diagnosis of paediatric brain infections, characterization of various patterns of brain involvement and establishing the differential diagnosis along with role of Diffusion Weighted Imaging and Apparent Diffusion Coefficient in Cerebral infections . Materials and methods: 50 cases with suspected brain infection, whose age group ranged from 0-14 years, referred to the Department of Radiodiagnosis and Imaging, Government Medical College, Amritsar, were included in this study. The sequences performed were T1W axial, T2W axial, coronal and saggital, FLAIR axial, DWI/ADC, SWI,post contrast T1W in all patients and magnetic resonance spectroscopy wherever required. MRI findings in all cases along with magnetic resonance spectroscopy, clinical and biochemical findings (wherever required) were taken into consideration to arrive at a diagnosis.