Acute pancreatitis is an acute inflammatory process of the pancreas with variable involvement of the pancreas, regional tissues around the pancreas, or remote organ systems. Acute pancreatitis is one of the most common causes of epigastric pain and numbers of studies have suggested that the disease may be increasing in incidence. The last two decades have seen the emergence of significant evidence that has altered certain aspects of the management of acute pancreatitis. While most cases of acute pancreatitis are mild, the challenge remains in managing the severe cases and the complications associated with acute pancreatitis. Gallstones are still the most common cause with epidemiological trends indicating a rising incidence. The surgical management of acute gallstone pancreatitis has evolved. The present study includes 60 cases of acute pancreatitis admitted in a tertiary care centre. The reason for this conduct was for the evaluation of the etiology, presenting symptoms, investigations, management and complications of acute pancreatitis in a rural set up. Once the diagnosis is made, clinical efforts should simultaneously concentrate on investigating for the underlying etiology and managing the condition by anticipating its complications. Management of acute pancreatitis is largely supportive.