Viruses cause familiar infections and diseases like common cold, flu. They invade living, normal cells and use those cells to multiply and produce colonies of cells.Viral infection is a proliferation of harmful viruses inside the body. Viruses infect the host body by introducing their genetic material into the cells. The main aim of this study is to explore detailed information about saliva and viral infections. This research is seen as a scoping literature review. In seeking to identify the relevant articles, we used common databases such as the Pubmed and Google scholar online websites. Totally 27 articles are found related to the topic. 12 articles are used in this study. From the articles collected and reviewed, it is understood that viral infections can transmit through the saliva and oral specimens, though saliva protects the body from infections. It is concluded that, as saliva has become the transmitter of the virus, we should maintain proper oral hygiene and oral health to prevent these viruses. Future studies have to be done on the viral infections causing cancer.