Aim and Objective: Orthodontic diagnosis and treatment planning for growing children must involve growth prediction, especially in the treatment of skeletal problems.The aim of this study was to correlate the growth phase of skeletal tissues with the calcification stages of maxillary canine, mandibular second molar and mandibular third molar. Materials and Methods: Anonymized digital Orthopantomogram and lateral cephalogram records of 50 pretreatment orthodontic patients aged 8–19 years were collected and analyzed. Right maxillary canine, mandibular second molar and third molar were used as a sample in accordance to the Gleiser and Hunt modified method of assessing tooth mineralization. The skeletal maturation was assessed by the cervical vertebrae maturation (CVMI) method by Baccetti et al. Results: A positive significant correlation was attained relating CVMI Stages 2,3 and 4 with calcification Stages maxillary canine, mandibular second molar and mandibular third molar.Conclusion: The calcification stages of maxillary canine, mandibular second molar and mandibular third molar can be implemented for assessing the skeletal maturity clinically. The canine calcification could be used as a sole indicator for assessment of skeletal maturity.