Online ISSN: 2515-8260

SQUAMOUS CELL CARCINOMA IN YOUNGER POPULATION: A SYSTEMIC REVIEW AND META ANALYSIS

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Dr. Swati Chaturvedi1 ,Dr. Dilber Pareed K2 ,Dr. Pranoti Hiralkar3 ,Dr. Sai Subramanian4 ,Dr. I Nalini Sailaja5 ,Dr. Vikesh Kumar R Shah6

Abstract

Introduction: Squamous cell carcinoma (SCC)s specifically of the tongue usually is seen in the senile population with a long standing tobacco habit. But recently the trend has changed to incidence of TSCC in younger adults with no risk factors. Hence we aim to conduct a systemic review and metanalyse to assess the prevalence and risk factors of tongue carcinoma in the younger group of patients. Materials and methods: We conducted the search for the data from the online sources like the “EMBASE”, “Pubmed”, “Scopus” and other sources. Only human studies were collected. Terms searched were CBCT, microtomography, permanent teeth, and root canal morphology. The data extraction and meta-analysis were based on the PRISMA guidelines. Out of the 109 articles, only 23 were selected based on the inclusion and exclusion criteria. For the assessment of the risk factors and the variables the statistical analysis was done keeping p<0.05 as significant. Results: we observed that most of the subjects were at ages 30-50 years. The majority of reports were <40 years of age. Almost equal gender distribution was seen. No association between the habits was seen in the younger adults. Conclusion: Prognosis of younger adults is poor than the older patients with the TSCC. Hence, evaluation of the etiology along with other risk factors exposure is expected. It can be proposed that identification of the potential risk factors aside from traditional factors is vital to control the incidence of TSCC in young patients.

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