The main reason for this high mortality is the lack of proper diagnosis at the right time. This is particularly important in patients with HIV and TB co-infection; especially with extra pulmonary TB as the detection rates are low. There is an urgent need to implement newer diagnostic modalities for the detection of TB especially in highly HIV prevalent areas. Patients satisfying inclusion criteria i.e. HIV positive patients clinically and/or radiologically suspected of pulmonary tuberculosis whose sputum AFB is reported negative were subjected for CBNAAT. This was done with the intention of identifying yield of CBNAAT over microscopy. Among patients with abnormal chest x-ray, 84.6% had positive CBNAAT while in those with normal chest X-ray, 81.1% had negative CBNAAT. Hence majority of patients with abnormal chest X-ray findings had positive CBNAAT while majority of those with normal chest x-ray had negative CBNAAT.