The study was conducted with the aim of detecting the causes of vaginitis infection in women and testing the efficacy of some antifungal compounds in treating the disease and the resistance of the isolated types of these antifungals. The study included isolating 125 samples using swabs for women with symptoms of injury in the cities of Al-Hilla and AlDiwanyia for the period from September 2019 to December 2019. The results showed that the rate of 73% was fungal infection and 25.4% non-fungal infection C.albicans is resistance to against the antifungals, as 6 isolates resistant to fluconazol and nystatin were obtained. While these isolates were sensitive to cherrybark oak plant extract