According to the World Health Organization, more than two-thirds (70%) of the global population will die from non-communicable diseases such as cancer, heart disease, stroke and diabetes. In the United States, stroke is the number five cause of death and a major cause of serious disability for adults. There are around 795,000 people in the United States who suffer a stroke every year. Based on the diagnosis in the population aged > 15 years from 2013-2018, the prevalence of stroke in Indonesia has increased for the stroke sufferers. Aim: This study aims to analyze the risk factors that influence stroke at the productive ages in Indonesia in 2014. Method:The research design was observational analytic with cross sectional approach. This study took place in Indonesia with the secondary data from the Indonesia Family Life Survey (IFLS) Edition 5. The dependent variable is stroke itself, while the independent variables are age, sex, smoking status and the history of hypertension. The population in this study was all Indonesian citizens who became the respondents in the Indonesia Family Life Survey (IFLS) which was conducted in 13 of 33 Provinces. The sample of this research was the population aged > 15-59 years (productive age) and fulfilled the inclusion criteria; the data that was filled and processed was complete data, so it obtained 1,253,027 respondents.Results:Respondents aged 51-59 have 1.6 times risk of stroke. Men are 0.8 times less risky than women. Respondents who once smoked are 1.6 times more likely to have a stroke than those who smoke. Hypertension respondents have 2.5 times risk of stroke than those who are not. Conclusion:There is an influence between the factors of age, sex, smoking history and hypertension on the incidence of stroke