To figure out how well pre-operative (neo-adjuvant) chemo-radiotherapy works for patients with locally advanced rectal cancer by looking at the rates of radiation enteritis after both preoperative and post-operative treatment. Follow-up continues until November 2019. The research required appropriate biochemistry, pathology, radiography, and medical/surgical management. Since June 2019, outpatients are assessed. Rectal cancer research studied age, sex, diagnosis delay, mortality, treatment options, death causes, surgical complications, and hospital stay. Typical, pre-validated, semi-structured case record proformas recorded the data