Background: Alcoholism is a severe hazard to both individuals and society, and the family bears the brunt of the disease's burden. Aims and objectives: 1. To study the sociodemographic profile of patient of alcohol dependence. 2. To study the psychiatric comorbidity in patients with alcohol dependence. 3. To study the quality of life in patients of alcohol dependence. 4. To study the caregiver’s burden in family members of alcohol dependence. Material and methods: The present study was conducted at Swami Vivekananda Drug De-addiction and Treatment Centre under Department of Psychiatry, Government Medical College, Amritsar with the primary purpose of determining the Psychiatric comorbidities, Quality of life in patients of Alcohol Dependence and Caregiver burden among their family members. For this purpose, minimum 100 patients of alcohol dependence syndrome who were admitted in Swami Vivekananda Drug De-addiction and Treatment Centre and their respective key caregivers during a period of 1 year from 2020 to 2021 will be selected and studied. The nature and purpose of the study was explained to the patients and their respective caregivers and an informed consent was taken from each of them. After Certain set of questions were asked from annexures and accompanying clinical assessment was done. Enrolled patients and their caregivers were assured of confidentiality of the information given by them and data assimilated was analyzed using standard methods